increased heart weight

295

significant genes

3.85%

of tested genes

7672

tested genes

greater than average weight of the heart compared to controls

Significant gene-phenotype associationsView data

IMPC Gene variants with increased heart weight

Total number of significant genotype-phenotype associations: 299



Epb41l4a *Epb41l4a^{tm1b(KOMP)Mbp}*	increased heart weight	Supporting data	homozygote	Early adult	Heart weight Heart Weight	JAX JAX	1.69x10^-6
Lcn2 *Lcn2^{tm1b(KOMP)Wtsi}*	increased heart weight	Supporting data	homozygote	Early adult	Heart weight Heart Weight	JAX JAX	5.05x10^-9
Slitrk2 *Slitrk2^em1(IMPC)Mbp*	increased heart weight	Supporting data	hemizygote	Early adult	Heart weight Heart Weight	UC Davis DTCC	6.23x10^-8
Cenpo *Cenpo^{tm1b(KOMP)Mbp}*	increased heart weight	Supporting data	heterozygote	Early adult	Heart weight Heart Weight	JAX JAX	2.74x10^-8
Trappc2l *Trappc2l^em1(IMPC)Mbp*	increased heart weight	Supporting data	homozygote	Early adult	Heart weight Heart Weight	UC Davis DTCC	2.86x10^-10
Afg1l *Afg1l^{em1(IMPC)Kmpc}*	increased heart weight	Supporting data	homozygote	Late adult	Heart weight Heart Weight	KMPC KMPC	1.33x10^-6
Cyb561 *Cyb561^{tm1b(EUCOMM)Wtsi}*	increased heart weight	Supporting data	homozygote	Early adult	Heart weight Organ Weight	MRC Harwell MRC	8.98x10^-5
Hsf4 *Hsf4^{tm1b(KOMP)Wtsi}*	increased heart weight	Supporting data	homozygote	Early adult	Heart weight Heart Weight	JAX JAX	6.5x10^-5
Mybpc3 *Mybpc3^{tm1a(EUCOMM)Hmgu}*	increased heart weight	Supporting data	homozygote	Early adult	Heart weight Heart weight/tibia length	MRC Harwell EUMODIC	4.78x10^-27
Pde2a *Pde2a^em1(IMPC)H*	increased heart weight	Supporting data	heterozygote	Early adult	Heart weight Organ Weight	MRC Harwell MRC	1.61x10^-5

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Not significant Significant Manual associations

Significant P-value threshold (P < 0.0001)

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Associations appearing in the region of 1x10^-30 are manually annotated as significant.

Click on a point of the chart to see the details of an association.

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