Trappc2l | trafficking protein particle complex 2L
Physiological systems
20 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system
11 No significant impact
4 Not tested
Data collections
Gene metrics:18Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased heart weight | 2 supporting datasets | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | 2.86x10-10 | ||
| abnormal bone structure | 1 supporting dataset | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | 4.06x10-6 | ||
| decreased bone mineral content | 2 supporting datasets | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | 3.4x10-10 | ||
| enlarged spleen | 2 supporting datasets | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small testis | 1 supporting dataset | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal testis morphology | 1 supporting dataset | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased prepulse inhibition | 3 supporting datasets | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | 1.31x10-8 | ||
| decreased body length | 1 supporting dataset | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | 3.55x10-5 | ||
| increased mean platelet volume | 1 supporting dataset | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | 2.28x10-5 | ||
| female infertility | 1 supporting dataset | Trappc2lem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Trappc2l mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Trappc2l.
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| Trappc2lem1(IMPC)Mbp | Exon Deletion | | mouse |
| Trappc2ltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |