Mybpc3 | myosin binding protein C, cardiac

GeneMGI:102844Synonyms: cardiac C-protein

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Cardiovascular system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased heart weight	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.78x10^-27
abnormal heart morphology	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.08x10^-5
increased circulating potassium level	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.43x10^-5
abnormal response to new environment	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	6.9x10^-5
decreased circulating amylase level	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.4x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mybpc3.

Associated images

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Histopathology

There is no histopathology data found for Mybpc3.

IMPC related publications

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External links

No external links available for Mybpc3.

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*Mybpc3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mybpc3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mybpc3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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