Mybpc3 | myosin binding protein C, cardiac

GeneMGI:102844Synonyms: cardiac C-protein

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Cardiovascular system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased heart weight	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.78x10^-27
abnormal heart morphology	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.08x10^-5
increased circulating potassium level	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.43x10^-5
abnormal response to new environment	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	6.9x10^-5
decreased circulating amylase level	1 supporting dataset	Mybpc3^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.4x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Mybpc3.

Associated images

Loading...

Histopathology

There is no histopathology data found for Mybpc3.

IMPC related publications

Loading...

External links

No external links available for Mybpc3.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Mybpc3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mybpc3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mybpc3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes