Slitrk2 | SLIT and NTRK-like family, member 2

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Growth/size/body region Behavior/neurological Cardiovascular system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased heart weight2 supporting datasetsSlitrk2em1(IMPC)MbphemizygoteEarly adult6.23x10-8 
enlarged ovary1 supporting datasetSlitrk2em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged epididymis1 supporting datasetSlitrk2em1(IMPC)MbphemizygoteEarly adultN/A * 
enlarged uterus1 supporting datasetSlitrk2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal ovary morphology1 supporting datasetSlitrk2em1(IMPC)MbphomozygoteEarly adultN/A * 
increased exploration in new environment1 supporting datasetSlitrk2em1(IMPC)MbphomozygoteEarly adult0 
decreased thigmotaxis2 supporting datasetsSlitrk2em1(IMPC)MbphemizygoteEarly adult1.63x10-5 
increased exploration in new environment1 supporting datasetSlitrk2em1(IMPC)MbphemizygoteEarly adult1.85x10-10 
abnormal uterus morphology1 supporting datasetSlitrk2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slitrk2em1(IMPC)MbpWhole-gene deletionmouse
Slitrk2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell

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