Cyb561 | cytochrome b-561

Physiological systems

22 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Adipose tissue Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Skeleton Craniofacial Cardiovascular system

10 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:38Significant phenotypes

1Associated diseases

Expression examined in:50Adult tissues

42Embryo tissues

Phenotypes

Allele:

Phy. System:



increased heart weight	1 supporting dataset	Cyb561^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.98x10^-5
increased erythrocyte cell number	1 supporting dataset	Cyb561^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.55x10^-5
decreased circulating total protein level	1 supporting dataset	Cyb561^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.17x10^-9
increased hematocrit	1 supporting dataset	Cyb561^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.63x10^-5
increased total body fat amount	2 supporting datasets	Cyb561^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.72x10^-10
tremors	1 supporting dataset	Cyb561^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.18x10^-12
increased hemoglobin content	1 supporting dataset	Cyb561^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.17x10^-5
abnormal cranium morphology	1 supporting dataset	Cyb561^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.23x10^-6
abnormal response to new environment	1 supporting dataset	Cyb561^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.77x10^-5
increased circulating triglyceride level	1 supporting dataset	Cyb561^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.31x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cyb561.

Associated images

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Histopathology

There is no histopathology data found for Cyb561.

IMPC related publications

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External links

No external links available for Cyb561.

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*Cyb561^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Cyb561^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Cyb561^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cyb561^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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