Afg1l | AFG1 like ATPase

GeneMGI:2148801Synonyms: Lace1

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Pigmentation Integument Growth/size/body region Vision/eye Behavior/neurological Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased heart weight	1 supporting dataset	Afg1l^{em1(IMPC)Kmpc}	homozygote	Late adult	1.33x10^-6
abnormal coat/hair pigmentation	2 supporting datasets	Afg1l^{em1(IMPC)Kmpc}	homozygote	Late adult	1.19x10^-7
hyperactivity	3 supporting datasets	Afg1l^{em1(IMPC)Kmpc}	homozygote	Late adult	3.94x10^-7
abnormal coat/hair pigmentation	2 supporting datasets	Afg1l^{em1(IMPC)Kmpc}	homozygote	Middle aged adult	4.93x10^-9
cornea vascularization	1 supporting dataset	Afg1l^{em1(IMPC)Kmpc}	homozygote	Late adult	8.2x10^-5
abnormal coat/ hair morphology	1 supporting dataset	Afg1l^{em1(IMPC)Kmpc}	homozygote	Late adult	8.01x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Afg1l.

Associated images

Loading...

Histopathology

There is no histopathology data found for Afg1l.

IMPC related publications

Loading...

External links

No external links available for Afg1l.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Afg1l^{em1(IMPC)Kmpc}*	Exon Deletion	‌	mouse
*Afg1l^{tm381003(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes