Pde2a | phosphodiesterase 2A, cGMP-stimulated
GeneMGI:2446107
Physiological systems
16 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Mortality/aging Cardiovascular system
10 No significant impact
8 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased heart weight | 1 supporting dataset | Pde2aem1(IMPC)H | heterozygote | Early adult | 1.61x10-5 | ||
| increased neutrophil cell number | 1 supporting dataset | Pde2aem1(IMPC)H | heterozygote | Early adult | 5.64x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pde2aem1(IMPC)H | homozygote | Early adult | N/A * | ||
| increased circulating bilirubin level | 1 supporting dataset | Pde2aem1(IMPC)H | heterozygote | Early adult | 5.18x10-5 |
| | | | | | | | | | |
External links
No external links available for Pde2a.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Pde2aem1(IMPC)H | Exon Deletion | | mouse |
| Pde2aem2(IMPC)H | Exon Deletion | | mouse |
| Pde2aem3H | Point Mutation | | mouse |
| Pde2aem4H | Point Mutation | | mouse |
| Pde2atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pde2atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Pde2atm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pde2atm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |