Epb41l4a | erythrocyte membrane protein band 4.1 like 4a

GeneMGI:103007Synonyms: Epb4.1l4a, NBL4

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

12 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

increased heart weight1 supporting datasetEpb41l4atm1b(KOMP)MbphomozygoteEarly adult1.69x10-6 
abnormal kidney morphology1 supporting datasetEpb41l4atm1b(KOMP)MbphomozygoteEarly adultN/A * 
decreased grip strength2 supporting datasetsEpb41l4atm1b(KOMP)MbphomozygoteEarly adult2.8x10-5 
decreased circulating glucose level1 supporting datasetEpb41l4atm1b(KOMP)MbphomozygoteEarly adult1.3x10-5 
increased mean corpuscular hemoglobin1 supporting datasetEpb41l4atm1b(KOMP)MbphomozygoteEarly adult9.75x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Epb41l4atm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Epb41l4atm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Epb41l4atm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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