decreased circulating bilirubin level
41
significant genes0.57%
of tested genes7156
tested genesDescription
reduced concentration in the blood of the bile pigment bilirubin, normally found in the liver and in red blood cells
Significant gene-phenotype associationsView data
IMPC Gene variants with decreased circulating bilirubin level
Total number of significant genotype-phenotype associations: 43
| Thap12 Thap12em1(IMPC)J | decreased circulating bilirubin level | Supporting data | heterozygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 4.65x10-9 | |
| Fbrs Fbrsem1(IMPC)J | decreased circulating bilirubin level | Supporting data | heterozygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 2.45x10-10 | |
| Ssh2 Ssh2em1(IMPC)J | decreased circulating bilirubin level | Supporting data | homozygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 5.94x10-5 | |
| Zmynd12 Zmynd12em1(IMPC)J | decreased circulating bilirubin level | Supporting data | homozygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 2.89x10-9 | |
| Or1e1c Or1e1cem1(IMPC)Mbp | decreased circulating bilirubin level | Supporting data | homozygote | Late adult | Total bilirubin Clinical Chemistry | UC Davis DTCC | 6.26x10-5 | |
| Timm17b Timm17bem1(IMPC)J | decreased circulating bilirubin level | Supporting data | hemizygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 1.31x10-5 | |
| Cog8 Cog8em1(IMPC)J | decreased circulating bilirubin level | Supporting data | heterozygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 1.53x10-7 | |
| Igfbp6 Igfbp6em1(IMPC)J | decreased circulating bilirubin level | Supporting data | homozygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 9.56x10-5 | |
| Tram1 Tram1em1(IMPC)J | decreased circulating bilirubin level | Supporting data | homozygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 5.31x10-5 | |
| Znhit2 Znhit2em1(IMPC)J | decreased circulating bilirubin level | Supporting data | heterozygote | Early adult | Total bilirubin Clinical Chemistry | JAX JAX | 1.49x10-5 |
Most significant associations for decreased circulating bilirubin level
Not significant Significant Manual associations
Significant P-value threshold (P < 0.0001)
Significant P-value threshold (P < 0.0001)
Associations details of selected gene(s):
Click on a point of the chart to see the details of an association.The way we measure
Procedure