Tram1 | translocating chain-associating membrane protein 1

GeneMGI:1919515Synonyms: TRAMP, 1810049E02Rik

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Behavior/neurological Skeleton Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	9 supporting datasets	Tram1^em1(IMPC)J	homozygote	Early adult	6.15x10^-7
decreased circulating bilirubin level	1 supporting dataset	Tram1^em1(IMPC)J	homozygote	Early adult	5.31x10^-5
increased blood urea nitrogen level	1 supporting dataset	Tram1^em1(IMPC)J	homozygote	Early adult	7.54x10^-10
abnormal bone structure	1 supporting dataset	Tram1^em1(IMPC)J	homozygote	Early adult	1.01x10^-7
decreased startle reflex	1 supporting dataset	Tram1^em1(IMPC)J	homozygote	Early adult	3.86x10^-7
increased total body fat amount	2 supporting datasets	Tram1^em1(IMPC)J	homozygote	Early adult	1.58x10^-18
decreased bone mineral content	2 supporting datasets	Tram1^em1(IMPC)J	homozygote	Early adult	2.39x10^-13
decreased lean body mass	2 supporting datasets	Tram1^em1(IMPC)J	homozygote	Early adult	6.2x10^-12
decreased heart weight	1 supporting dataset	Tram1^em1(IMPC)J	homozygote	Early adult	7.86x10^-5
decreased circulating total protein level	1 supporting dataset	Tram1^em1(IMPC)J	homozygote	Early adult	2.15x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Tram1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Tram1.

IMPC related publications

Loading...

External links

No external links available for Tram1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Tram1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Tram1^{tm84704(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes