Igfbp6 | insulin-like growth factor binding protein 6

GeneMGI:96441Synonyms: IGFBP-6

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



decreased circulating bilirubin level	1 supporting dataset	Igfbp6^em1(IMPC)J	homozygote	Early adult	9.56x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Igfbp6^em1(IMPC)J	homozygote	Early adult	1.56x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Igfbp6.

Associated images

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Histopathology

There is no histopathology data found for Igfbp6.

IMPC related publications

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External links

No external links available for Igfbp6.

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*Igfbp6^em1(IMPC)J*	Exon Deletion	‌	mouse
*Igfbp6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Igfbp6^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Igfbp6^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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