Znhit2 | zinc finger, HIT domain containing 2

GeneMGI:1352481Synonyms: Znhit2-ps, ORF6

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Znhit2^em1(IMPC)J	homozygote	E9.5	N/A ^*
decreased circulating bilirubin level	1 supporting dataset	Znhit2^em1(IMPC)J	heterozygote	Early adult	1.49x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Znhit2^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased circulating glucose level	1 supporting dataset	Znhit2^em1(IMPC)J	heterozygote	Early adult	2.01x10^-8
increased leukocyte cell number	1 supporting dataset	Znhit2^em1(IMPC)J	heterozygote	Early adult	1.66x10^-5
increased grip strength	1 supporting dataset	Znhit2^em1(IMPC)J	heterozygote	Early adult	5.46x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Znhit2.

Associated images

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Histopathology

There is no histopathology data found for Znhit2.

IMPC related publications

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External links

No external links available for Znhit2.

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*Znhit2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Znhit2^{tm463803(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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