Fbrs | fibrosin
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Mortality/aging
14 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating bilirubin level | 1 supporting dataset | Fbrsem1(IMPC)J | heterozygote | Early adult | 2.45x10-10 | ||
| abnormal cholesterol homeostasis | 1 supporting dataset | Fbrsem1(IMPC)J | heterozygote | Early adult | 3.68x10-17 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Fbrsem1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased circulating bilirubin level | 1 supporting dataset | Fbrsem1(IMPC)J | heterozygote | Early adult | 1.77x10-5 | ||
| cataract | 1 supporting dataset | Fbrsem1(IMPC)J | heterozygote | Early adult | 1.73x10-5 | ||
| decreased circulating alanine transaminase level | 1 supporting dataset | Fbrsem1(IMPC)J | heterozygote | Early adult | 1.68x10-8 | ||
| decreased circulating alkaline phosphatase level | 1 supporting dataset | Fbrsem1(IMPC)J | heterozygote | Early adult | 5.39x10-5 | ||
| decreased circulating aspartate transaminase level | 1 supporting dataset | Fbrsem1(IMPC)J | heterozygote | Early adult | 4.71x10-12 |
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External links
No external links available for Fbrs.
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| Fbrsem1(IMPC)J | Exon Deletion | | mouse |
| Fbrstm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |