cataract
353
significant genes4.53%
of tested genes7792
tested genesDescription
complete or partial opacity of the lens
Significant gene-phenotype associationsView data
IMPC Gene variants with cataract
Total number of significant genotype-phenotype associations: 358
| Greb1l Greb1lem1(IMPC)J | cataract | Supporting data | heterozygote | Early adult | Lens Opacity Eye Morphology | JAX JAX | 2.63x10-5 | |
| Fam83b Fam83bem1(IMPC)Mbp | cataract | Supporting data | homozygote | Early adult | Lens Opacity Eye Morphology | UC Davis DTCC | 6.35x10-5 | |
| Cdk2ap2 Cdk2ap2em1(IMPC)J | cataract | Supporting data | homozygote | Early adult | Lens Opacity Eye Morphology | JAX JAX | 3.5x10-6 | |
| Cbr2 Cbr2tm1b(EUCOMM)Hmgu | cataract | Supporting data | homozygote | Early adult | Lens Opacity Eye Morphology | WTSI MGP | 6.7x10-5 | |
| Fam216a Fam216atm1b(EUCOMM)Hmgu | cataract | Supporting data | homozygote | Early adult | Lens Opacity Eye Morphology | HMGU Helmholtz GMC | 1.37x10-7 | |
| Prc1 Prc1tm1b(EUCOMM)Hmgu | cataract | Supporting data | heterozygote | Early adult | Lens Opacity Eye Morphology | HMGU Helmholtz GMC | 2.29x10-10 | |
| Trp53inp2 Trp53inp2em1(IMPC)Mbp | cataract | Supporting data | homozygote | Early adult | Lens Opacity Eye Morphology | UC Davis DTCC | 2.8x10-7 | |
| Trim13 Trim13em1(IMPC)Tcp | cataract | Supporting data | homozygote | Late adult | Lens Opacity Eye Morphology | TCP DTCC | 1.76x10-7 | |
| Angptl1 Angptl1tm4b(KOMP)Wtsi | cataract | Supporting data | homozygote | Early adult | Lens Opacity Eye Morphology | KMPC KMPC | 6.12x10-6 | |
| Actg2 Actg2em1(IMPC)J | cataract | Supporting data | homozygote | Early adult | Lens Opacity Eye Morphology | JAX JAX | 5.21x10-7 |
Most significant associations for cataract
Not significant Significant Manual associations
Significant P-value threshold (P < 0.0001)
Significant P-value threshold (P < 0.0001)