Cbr2 | carbonyl reductase 2

GeneMGI:107200Synonyms: lung carbonyl reductase, MLCR

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetCbr2tm1b(EUCOMM)HmguhomozygoteEarly adult6.7x10-5 
decreased circulating amylase level1 supporting datasetCbr2tm1b(EUCOMM)HmguhomozygoteEarly adult3.6x10-11 
decreased circulating fructosamine level1 supporting datasetCbr2tm1b(EUCOMM)HmguhomozygoteEarly adult5.76x10-6 
abnormal lens morphology1 supporting datasetCbr2tm1b(EUCOMM)HmguhomozygoteEarly adult6.7x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cbr2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Cbr2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cbr2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cbr2tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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