Angptl1 | angiopoietin-like 1

GeneMGI:1919963Synonyms: ANG-3, 2810039D03Rik, +4 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetAngptl1tm4b(KOMP)WtsihomozygoteEarly adult6.12x10-6 
abnormal lens morphology1 supporting datasetAngptl1tm4b(KOMP)WtsihomozygoteEarly adult6.12x10-6 
hyperactivity3 supporting datasetsAngptl1tm4b(KOMP)WtsihomozygoteEarly adult4.5x10-6 
increased blood urea nitrogen level1 supporting datasetAngptl1tm4b(KOMP)WtsihomozygoteEarly adult8.92x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Angptl1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Angptl1tm106048(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Angptl1tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Angptl1tm4a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Angptl1tm4b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Angptl1tm4e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Angptl1tm5e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Angptl1tm6e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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