Prc1 | protein regulator of cytokinesis 1
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Adipose tissue Vision/eye Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| cataract | 1 supporting dataset | Prc1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.29x10-10 | ||
| abnormal retina morphology | 1 supporting dataset | Prc1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.77x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Prc1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| increased total body fat amount | 2 supporting datasets | Prc1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.11x10-5 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Prc1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.16x10-5 | ||
| abnormal lens morphology | 1 supporting dataset | Prc1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.07x10-11 |
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Human diseases caused by Prc1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Prc1.
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