Greb1l | growth regulation by estrogen in breast cancer-like
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Adipose tissue Embryo Growth/size/body region Nervous system Vision/eye Mortality/aging
12 No significant impact
6 Not tested
Data collections
Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| cataract | 1 supporting dataset | Greb1lem1(IMPC)J | heterozygote | Early adult | 2.63x10-5 | ||
| embryonic growth retardation | 1 supporting dataset | Greb1lem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Greb1lem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| decreased lean body mass | 2 supporting datasets | Greb1lem1(IMPC)J | heterozygote | Early adult | 5.4x10-8 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Greb1lem1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal embryo turning | 1 supporting dataset | Greb1lem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| increased total body fat amount | 1 supporting dataset | Greb1lem1(IMPC)J | heterozygote | Early adult | 7.8x10-11 |
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External links
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| Greb1lem1(IMPC)J | Exon Deletion | | mouse |
| Greb1ltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Greb1ltm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Greb1ltm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Greb1ltm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |