A Clinical Chemistry phenotypic assay was performed on 1057 mice. The charts show the results of measuring Alkaline phosphatase in 10 female, 9 male mutants compared to 553 female, 485 male controls. The mutants are for the Bdkrb1em1(IMPC)H allele.
increased circulating alkaline phosphatase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Alkaline phosphatase | MRC Harwell | Bdkrb1em1(IMPC)H | homozygote | Late adult | H-BDKRB1-DEL28-EM1-B6N | 6.09x10-1 | 1.49x10-5 | 1.49x10-5 | |
Bdkrb1 data charts
Alkaline phosphataseExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alkaline phosphatase
Testing environment
Lab conditions and equipment
Life stage
Late adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Alkaline phosphatase / Box plot
Alkaline phosphatase / Scatter plot
Results of statistical analysis
Genotype P value
1.49x10-5
Genotype*Female P value
1.49x10-5
Genotype*Male P value
6.09x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 1.48645684775608e-05 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | false |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 1.49x10-5 |
| Genotype parameter estimate | -60.322 |
| Genotype standard error estimate | 7.675 |
| Genotype Effect P Value | 1.49x10-5 |
| Sex Parameter Estimate | -60.322 |
| Sex Standard Error Estimate | 4.965 |
| Sex Effect P Value | 1.49x10-5 |
| Intercept Estimate | 96.791 |
| Intercept Estimate Standard Error | 15.779 |
| Sex Male KO P Value | 1.49x10-5 |
| Sex Female KO P Value | 1.49x10-5 |
| WT Residuals Normality Tests | 6.24x10-6 |
| KO Residuals Normality Tests | 1.47x10-4 |
Statistical analysis API access
Experimental data download
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