A Hematology phenotypic assay was performed on 962 mice. The charts show the results of measuring Mean corpuscular hemoglobin in 7 female, 7 male mutants compared to 484 female, 464 male controls. The mutants are for the Etaa1em1(IMPC)Marc allele.
decreased mean corpuscular hemoglobin
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Mean corpuscular hemoglobin | MARC | Etaa1em1(IMPC)Marc | homozygote | Early adult | Etaa1_cas9_del22 | 3.33x10-8 | 5.01x10-1 | 4.5x10-1 | |
Etaa1 data charts
Mean corpuscular hemoglobinExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Mean corpuscular hemoglobin
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
MARC
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Mean corpuscular hemoglobin / Box plot
Mean corpuscular hemoglobin / Scatter plot
Results of statistical analysis
Genotype P value
4.5x10-1
Genotype*Female P value
5.01x10-1
Genotype*Male P value
3.33x10-8
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.450490214662187 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 4.5x10-1 |
| Genotype parameter estimate | -0.162 |
| Genotype standard error estimate | 0.210 |
| Genotype Effect P Value | 4.5x10-1 |
| Sex Parameter Estimate | -0.162 |
| Sex Standard Error Estimate | 0.034 |
| Sex Effect P Value | 4.5x10-1 |
| Intercept Estimate | 12.624 |
| Intercept Estimate Standard Error | 0.048 |
| Sex Male KO P Value | 4.5x10-1 |
| Sex Female KO P Value | 4.5x10-1 |
| WT Residuals Normality Tests | 8.53x10-29 |
| KO Residuals Normality Tests | 9.98x10-1 |
Statistical analysis API access
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