A Clinical Chemistry phenotypic assay was performed on 176 mice. The charts show the results of measuring Calcium in 7 female, 7 male mutants compared to 79 female, 83 male controls. The mutants are for the Tmem100tm1e.1(KOMP)Wtsi allele.
decreased circulating calcium level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Calcium | TCP | Tmem100tm1e.1(KOMP)Wtsi | heterozygote | Early adult | TCPA0049Cre | 7.39x10-6 | 2.74x10-1 | 2.54x10-1 | |
Tmem100 data charts
CalciumExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Calcium
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
TCP
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Calcium / Box plot
Calcium / Scatter plot
Results of statistical analysis
Genotype P value
2.54x10-1
Genotype*Female P value
2.74x10-1
Genotype*Male P value
7.39x10-6
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.253863477307749 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | false |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 2.54x10-1 |
| Genotype parameter estimate | 0.134 |
| Genotype standard error estimate | 0.097 |
| Genotype Effect P Value | 2.54x10-1 |
| Sex Parameter Estimate | 0.134 |
| Sex Standard Error Estimate | 0.073 |
| Sex Effect P Value | 2.54x10-1 |
| Intercept Estimate | 9.685 |
| Intercept Estimate Standard Error | 0.050 |
| Sex Male KO P Value | 2.54x10-1 |
| Sex Female KO P Value | 2.54x10-1 |
| WT Residuals Normality Tests | 1.22x10-2 |
| KO Residuals Normality Tests | 1.98x10-1 |
Statistical analysis API access
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