Tmem100 | transmembrane protein 100

GeneMGI:1915138Synonyms: 1810057C19Rik

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Embryo Growth/size/body region Respiratory system Hematopoietic system Cardiovascular system Mortality/aging

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:43Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal pericardium morphology	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Tmem100^{tm1e.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
edema	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
pale yolk sac	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
abnormal lung morphology	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
increased leukocyte cell number	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	heterozygote	Early adult	1.2x10^-5
decreased circulating calcium level	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	heterozygote	Early adult	7.39x10^-6
increased lymphocyte cell number	1 supporting dataset	Tmem100^{tm1e.1(KOMP)Wtsi}	heterozygote	Early adult	6.29x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem100.

Associated images

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Histopathology

There is no histopathology data found for Tmem100.

IMPC related publications

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External links

No external links available for Tmem100.

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*Tmem100^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tmem100^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell mouse
*Tmem100^{tm1e.1(KOMP)Wtsi}*	Promoter excision from Targeted, non-conditional allele	‌	mouse
*Tmem100^{tm43147(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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