A Hematology phenotypic assay was performed on 1839 mice. The charts show the results of measuring Red blood cell distribution width in 7 female, 7 male mutants compared to 898 female, 927 male controls. The mutants are for the Gsta4tm1b(EUCOMM)Hmgu allele.
increased red blood cell distribution width
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Red blood cell distribution width | HMGU | Gsta4tm1b(EUCOMM)Hmgu | homozygote | Early adult | HMGU-HEPD0734_7_B08-1-1 | 3.3x10-8 | 3.63x10-1 | 4.2x10-1 | |
Gsta4 data charts
Red blood cell distribution widthExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Red blood cell distribution width
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
HMGU
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Red blood cell distribution width / Box plot
Red blood cell distribution width / Scatter plot
Results of statistical analysis
Genotype P value
4.2x10-1
Genotype*Female P value
3.63x10-1
Genotype*Male P value
3.3x10-8
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.420071798514903 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 4.2x10-1 |
| Genotype parameter estimate | 0.112 |
| Genotype standard error estimate | 0.151 |
| Genotype Effect P Value | 4.2x10-1 |
| Sex Parameter Estimate | 0.112 |
| Sex Standard Error Estimate | 0.052 |
| Sex Effect P Value | 4.2x10-1 |
| Intercept Estimate | 13.920 |
| Intercept Estimate Standard Error | 0.181 |
| Sex Male KO P Value | 4.2x10-1 |
| Sex Female KO P Value | 4.2x10-1 |
| WT Residuals Normality Tests | 9.13x10-10 |
| KO Residuals Normality Tests | 8.72x10-1 |
Statistical analysis API access
Experimental data download
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