Gsta4 | glutathione S-transferase, alpha 4

GeneMGI:1309515Synonyms: mGsta4, GST 5.7

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Pigmentation Integument Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



shortened PQ interval	1 supporting dataset	Gsta4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.17x10^-5
abnormal vitreous body morphology	1 supporting dataset	Gsta4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.68x10^-5
increased red blood cell distribution width	1 supporting dataset	Gsta4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.3x10^-8
decreased exploration in new environment	1 supporting dataset	Gsta4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.89x10^-5
abnormal coat/hair pigmentation	3 supporting datasets	Gsta4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.04x10^-6
abnormal lens morphology	1 supporting dataset	Gsta4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.19x10^-5
abnormal retina morphology	1 supporting dataset	Gsta4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.91x10^-5
increased startle reflex	1 supporting dataset	Gsta4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.51x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gsta4.

Associated images

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Histopathology

There is no histopathology data found for Gsta4.

IMPC related publications

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External links

No external links available for Gsta4.

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*Gsta4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gsta4^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gsta4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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