Histopathology data for Zfp106

Severity Score:

0 = Normal
1 = Mild (observation barely perceptible and not believed to have clinical significance)
2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical)
3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor)
4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.



Eye with optic nerve	heterozygote	#1	Involving one eye, there are clusters of external ...	N/A	1	0	localized	Retinal dysplasia
Thyroid	heterozygote	#1	N/A	N/A	0	0	N/A	N/A
Adrenal gland	heterozygote	#1	N/A	N/A	0	0	N/A	N/A
Spleen	heterozygote	#1	N/A	N/A	0	0	N/A	N/A
Bone marrow	heterozygote	#1	N/A	N/A	0	0	N/A	N/A
Brown adipose tissue	heterozygote	#1	There is focally extensive hyperplasia of brown fa...	N/A	1	0	chronic-active localized	Steatitis with hyperplasia
Epididymis	heterozygote	#1	N/A	N/A	0	0	N/A	N/A
Kidney	heterozygote	#1	N/A	N/A	0	0	N/A	N/A
Thymus	heterozygote	#1	N/A	N/A	0	0	N/A	N/A
Small intestine	heterozygote	#1	N/A	N/A	0	0	N/A	N/A

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