Gdi2 | GDP dissociation inhibitor 2

GeneMGI:99845Synonyms: Gdi3, GDIB, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Cardiovascular system Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina morphology	1 supporting dataset	Gdi2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.07x10^-6
cataract	1 supporting dataset	Gdi2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.42x10^-6
abnormal retina vasculature morphology	1 supporting dataset	Gdi2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.65x10^-5
abnormal lens morphology	1 supporting dataset	Gdi2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.1x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Gdi2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
impaired glucose tolerance	1 supporting dataset	Gdi2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.11x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gdi2.

Associated images

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Histopathology

There is no histopathology data found for Gdi2.

IMPC related publications

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External links

No external links available for Gdi2.

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*Gdi2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Gdi2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gdi2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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