Htr7 | 5-hydroxytryptamine (serotonin) receptor 7

GeneMGI:99841Synonyms: 5-HT7

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

25Embryo tissues

Phenotypes



increased circulating chloride level	1 supporting dataset	Htr7^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.28x10^-5
increased circulating sodium level	1 supporting dataset	Htr7^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.54x10^-6
decreased fasting circulating glucose level	1 supporting dataset	Htr7^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.12x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Htr7.

Associated images

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Histopathology

There is no histopathology data found for Htr7.

IMPC related publications

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External links

No external links available for Htr7.

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*Htr7^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Htr7^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Htr7^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Htr7^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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