Nt5e | 5' nucleotidase, ecto

GeneMGI:99782Synonyms: ecto-5'-nucleotidase, CD73, +2 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



cataract	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	6.35x10^-5
enlarged kidney	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged testis	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	5.99x10^-5
abnormal spleen morphology	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
urinary bladder obstruction	1 supporting dataset	Nt5e^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nt5e.

Associated images

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Histopathology

There is no histopathology data found for Nt5e.

IMPC related publications

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External links

No external links available for Nt5e.

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*Nt5e^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Nt5e^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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