Syt1 | synaptotagmin I

GeneMGI:99667Synonyms: G630098F17Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Skeleton Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased bone mineral content	1 supporting dataset	Syt1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.61x10^-5
decreased lean body mass	1 supporting dataset	Syt1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	9.57x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Syt1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Syt1.

Associated images

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Histopathology

There is no histopathology data found for Syt1.

IMPC related publications

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External links

No external links available for Syt1.

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*Syt1^{tm1(IMPC)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Syt1^{tm1.2(IMPC)Wtsi}*	Reporter-tagged deletion allele (post Flp, with no reporter and selection cassette)	‌	mouse
*Syt1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Syt1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Syt1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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