Epha3 | Eph receptor A3

GeneMGI:99612Synonyms: End3, Tyro4, +4 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Renal/urinary system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small spleen	1 supporting dataset	Epha3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
hyperactivity	2 supporting datasets	Epha3^em1(IMPC)Mbp	homozygote	Early adult	4.39x10^-7
decreased body length	1 supporting dataset	Epha3^em1(IMPC)Mbp	homozygote	Early adult	5.77x10^-5
abnormal liver morphology	2 supporting datasets	Epha3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small liver	2 supporting datasets	Epha3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Epha3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Epha3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Epha3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased anxiety-related response	1 supporting dataset	Epha3^em1(IMPC)Mbp	homozygote	Early adult	5.95x10^-5
decreased thigmotaxis	2 supporting datasets	Epha3^em1(IMPC)Mbp	homozygote	Early adult	6.66x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Epha3.

Associated images

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Histopathology

There is no histopathology data found for Epha3.

IMPC related publications

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External links

No external links available for Epha3.

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*Epha3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Epha3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Epha3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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