Pigh | phosphatidylinositol glycan anchor biosynthesis, class H
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues
embryonic lethality prior to organogenesis | 1 supporting dataset | Pightm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
decreased circulating HDL cholesterol level | 1 supporting dataset | Pightm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.29x10-5 | ||
increased circulating sodium level | 1 supporting dataset | Pightm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.29x10-6 | ||
increased grip strength | 1 supporting dataset | Pightm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.67x10-5 | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Pightm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Pightm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
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External links
No external links available for Pigh.
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Pightm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Pightm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Pightm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |