Pigf | phosphatidylinositol glycan anchor biosynthesis, class F

GeneMGI:99462

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Skeleton Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased lean body mass	1 supporting dataset	Pigf^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	1.79x10^-5
decreased bone mineral content	1 supporting dataset	Pigf^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	2.08x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Pigf^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased total body fat amount	1 supporting dataset	Pigf^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	2.3x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pigf.

Associated images

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Histopathology

There is no histopathology data found for Pigf.

IMPC related publications

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External links

No external links available for Pigf.

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*Pigf^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Pigf^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

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