Btc | betacellulin, epidermal growth factor family member

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

17 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal lymph node morphology1 supporting datasetBtcem1(IMPC)MbphomozygoteEarly adultN/A * 
increased neutrophil cell number1 supporting datasetBtcem1(IMPC)MbphomozygoteEarly adult3.88x10-6 
enlarged lymph nodes1 supporting datasetBtcem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Btcem1(IMPC)MbpExon Deletionmouse
Btctm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Btctm368640(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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