Cdh4 | cadherin 4

GeneMGI:99218Synonyms: R-cadherin, R-Cadh, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



increased circulating total protein level	1 supporting dataset	Cdh4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.15x10^-5
increased circulating sodium level	1 supporting dataset	Cdh4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.86x10^-7
decreased vertical activity	1 supporting dataset	Cdh4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.4x10^-7
abnormal motor coordination/balance	1 supporting dataset	Cdh4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.17x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cdh4.

Associated images

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Histopathology

There is no histopathology data found for Cdh4.

IMPC related publications

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External links

No external links available for Cdh4.

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*Cdh4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cdh4^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cdh4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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