Zscan21 | zinc finger and SCAN domain containing 21

GeneMGI:99182Synonyms: CTfin51, Zfp38, +3 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Integument Vision/eye Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal skin coloration	1 supporting dataset	Zscan21^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	5.72x10^-6
preweaning lethality, incomplete penetrance	2 supporting datasets	Zscan21^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased total retina thickness	2 supporting datasets	Zscan21^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	6.47x10^-8
abnormal retina inner nuclear layer morphology	2 supporting datasets	Zscan21^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	1.59x10^-5
male infertility	1 supporting dataset	Zscan21^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased total retina thickness	2 supporting datasets	Zscan21^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	7.71x10^-6
decreased respiratory quotient	1 supporting dataset	Zscan21^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	4.84x10^-6
female infertility	1 supporting dataset	Zscan21^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zscan21.

Associated images

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Histopathology

There is no histopathology data found for Zscan21.

IMPC related publications

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External links

No external links available for Zscan21.

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*Zscan21^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zscan21^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Zscan21^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Zscan21^{tm2b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Zscan21^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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