Xdh | xanthine dehydrogenase

GeneMGI:98973Synonyms: XO, xanthine oxidase, +3 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Integument Vision/eye Respiratory system

17 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology2 supporting datasetsXdhem1(IMPC)MbpheterozygoteEarly adultN/A * 
male infertility1 supporting datasetXdhem1(IMPC)MbphomozygoteEarly adultN/A * 
persistence of hyaloid vascular system1 supporting datasetXdhem1(IMPC)MbpheterozygoteEarly adult7.59x10-7 
abnormal vitreous body morphology1 supporting datasetXdhem1(IMPC)MbpheterozygoteEarly adult1.9x10-6 
cataract1 supporting datasetXdhem1(IMPC)MbpheterozygoteEarly adult2.2x10-6 
abnormal lung morphology1 supporting datasetXdhem1(IMPC)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Xdhem1(IMPC)MbpExon Deletionmouse
Xdhtm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Xdhtm428624(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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