Trf | transferrin

GeneMGI:98821Synonyms: HP, Tfn

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Adipose tissue Embryo Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



abnormal embryo size	1 supporting dataset	Trf^em1(IMPC)J	homozygote	E18.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Trf^em1(IMPC)J	homozygote	Early adult	N/A ^*
impaired righting response	1 supporting dataset	Trf^em1(IMPC)J	heterozygote	Late adult	3.62x10^-6
decreased circulating iron level	1 supporting dataset	Trf^{em1(IMPC)Rbrc}	heterozygote	Early adult	1.83x10^-5
abnormal locomotor behavior	1 supporting dataset	Trf^em1(IMPC)J	heterozygote	Late adult	2.27x10^-5
limb grasping	1 supporting dataset	Trf^em1(IMPC)J	heterozygote	Late adult	6.75x10^-7
pallor	1 supporting dataset	Trf^em1(IMPC)J	homozygote	E18.5	N/A ^*
increased mean corpuscular hemoglobin	1 supporting dataset	Trf^em1(IMPC)J	heterozygote	Late adult	9.27x10^-7
increased mean corpuscular volume	1 supporting dataset	Trf^em1(IMPC)J	heterozygote	Late adult	7.01x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Trf^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Trf.

Associated images

Loading...

Histopathology

There is no histopathology data found for Trf.

IMPC related publications

Loading...

External links

No external links available for Trf.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Trf^em1(IMPC)J*	Exon Deletion	‌	mouse
*Trf^{em1(IMPC)Rbrc}*	Exon Deletion	‌	mouse
*Trf^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Trf^{tm43021(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes