Thbd | thrombomodulin

GeneMGI:98736Synonyms: CD141, TM

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Respiratory system Mortality/aging

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

4Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased lung weight	1 supporting dataset	Thbd^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	8.33x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Thbd^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Thbd^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Thbd.

Associated images

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Histopathology

There is no histopathology data found for Thbd.

IMPC related publications

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External links

No external links available for Thbd.

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*Thbd^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Thbd^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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