Tg | thyroglobulin
Physiological systems
16 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Integument Hearing/vestibular/ear Behavior/neurological Skeleton Cardiovascular system
9 No significant impact
8 Not tested
Data collections
Gene metrics:12Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased grip strength | 2 supporting datasets | Tgem1(IMPC)J | homozygote | Early adult | 1.61x10-9 | ||
| abnormal coat/ hair morphology | 2 supporting datasets | Tgem1(IMPC)J | homozygote | Early adult | 1.57x10-5 | ||
| improved glucose tolerance | 1 supporting dataset | Tgem1(IMPC)J | homozygote | Early adult | 1.07x10-5 | ||
| abnormal auditory brainstem response | 1 supporting dataset | Tgem1(IMPC)J | homozygote | Early adult | 9.09x10-5 | ||
| decreased vertical activity | 1 supporting dataset | Tgem1(IMPC)J | homozygote | Early adult | 6.48x10-8 | ||
| decreased locomotor activity | 2 supporting datasets | Tgem1(IMPC)J | homozygote | Early adult | 9.71x10-6 | ||
| male infertility | 1 supporting dataset | Tgem1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased bone mineral content | 1 supporting dataset | Tgem1(IMPC)J | homozygote | Early adult | 5.04x10-15 | ||
| abnormal locomotor behavior | 1 supporting dataset | Tgem1(IMPC)J | homozygote | Early adult | 5.61x10-6 | ||
| prolonged RR interval | 1 supporting dataset | Tgem1(IMPC)J | homozygote | Early adult | 6.18x10-5 |
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External links
No external links available for Tg.
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| Tgem1(IMPC)J | Exon Deletion | | mouse |
| Tgtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |