Tbx3 | T-box 3
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Vision/eye Behavior/neurological Cardiovascular system Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Tbx3em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| eye hemorrhage | 1 supporting dataset | Tbx3em1(IMPC)Mbp | heterozygote | Early adult | 5.84x10-6 | ||
| decreased locomotor activity | 1 supporting dataset | Tbx3em1(IMPC)Mbp | heterozygote | Early adult | 1.49x10-5 | ||
| abnormal lymph node morphology | 1 supporting dataset | Tbx3em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Tbx3em1(IMPC)Mbp | heterozygote | Early adult | 1.82x10-5 | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Tbx3em1(IMPC)Mbp | heterozygote | Early adult | 6.32x10-5 | ||
| abnormal eye morphology | 1 supporting dataset | Tbx3em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Tbx3em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Tbx3em1(IMPC)Mbp | heterozygote | Early adult | 3.73x10-6 |
| | | | | | | | | | |
External links
No external links available for Tbx3.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Tbx3em1(IMPC)Mbp | Exon Deletion | | mouse |
| Tbx3tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |