Sptb | spectrin beta, erythrocytic
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Hematopoietic system Behavior/neurological Mortality/aging
15 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Sptbem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| decreased mean corpuscular volume | 1 supporting dataset | Sptbem1(IMPC)J | heterozygote | Early adult | 9.54x10-10 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Sptbem1(IMPC)J | homozygote | Early adult | N/A * | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Sptbem1(IMPC)J | heterozygote | Early adult | 6.26x10-17 | ||
| increased erythrocyte cell number | 1 supporting dataset | Sptbem1(IMPC)J | heterozygote | Early adult | 5.28x10-5 | ||
| decreased exploration in new environment | 1 supporting dataset | Sptbem1(IMPC)J | heterozygote | Early adult | 2.32x10-6 |
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External links
No external links available for Sptb.
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| Sptbem1(IMPC)J | Exon Deletion | | mouse |
| Sptbtm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Sptbtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sptbtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Sptbtm2(EGFP/cre/ERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |