Spn | sialophorin

GeneMGI:98384Synonyms: 3E8 antigen, Ly-48, +5 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Limbs/digits/tail Vision/eye Behavior/neurological Skeleton

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal behavior1 supporting datasetSpnem1(IMPC)IcshomozygoteEarly adult3.28x10-5 
long tibia1 supporting datasetSpnem1(IMPC)IcshomozygoteEarly adult3x10-6 
increased cornea thickness1 supporting datasetSpnem1(IMPC)IcshomozygoteEarly adult7.72x10-7 
increased total body fat amount2 supporting datasetsSpnem1(IMPC)IcshomozygoteEarly adult3x10-9 
decreased exploration in new environment1 supporting datasetSpnem1(IMPC)IcshomozygoteEarly adult8.2x10-6 
abnormal locomotor behavior1 supporting datasetSpnem1(IMPC)IcshomozygoteEarly adult1.36x10-5 
decreased lean body mass2 supporting datasetsSpnem1(IMPC)IcshomozygoteEarly adult5.25x10-11 
abnormal freezing behavior1 supporting datasetSpnem1(IMPC)IcshomozygoteEarly adult2.19x10-5 
increased body length1 supporting datasetSpnem1(IMPC)IcshomozygoteEarly adult2.64x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Spnem1(IMPC)IcsDeletionmouse
Spntm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Spntm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell

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