Sst | somatostatin

GeneMGI:98326Synonyms: Smst, preprosomatostatin, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Skeleton

13 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:152Adult tissues
25Embryo tissues

Phenotypes

decreased circulating alkaline phosphatase level1 supporting datasetSsttm1b(KOMP)WtsihomozygoteEarly adult4.87x10-6 
increased circulating serum albumin level1 supporting datasetSsttm1b(KOMP)WtsihomozygoteEarly adult3.02x10-12 
decreased bone mineral content1 supporting datasetSsttm1b(KOMP)WtsihomozygoteEarly adult5.41x10-6 
increased total body fat amount2 supporting datasetsSsttm1b(KOMP)WtsihomozygoteEarly adult9.16x10-17 
decreased lean body mass2 supporting datasetsSsttm1b(KOMP)WtsihomozygoteEarly adult2.53x10-7 
increased circulating iron level1 supporting datasetSsttm1b(KOMP)WtsihomozygoteEarly adult6.46x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ssttm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ssttm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ssttm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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