Pmel | premelanosome protein

GeneMGI:98301Synonyms: D12S53Eh, gp87, +4 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating bilirubin level	1 supporting dataset	Pmel^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.92x10^-5
increased startle reflex	1 supporting dataset	Pmel^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.32x10^-6
decreased total body fat amount	1 supporting dataset	Pmel^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.62x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pmel.

Associated images

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Histopathology

There is no histopathology data found for Pmel.

IMPC related publications

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External links

No external links available for Pmel.

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*Pmel^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pmel^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pmel^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pmel^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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