Scg5 | secretogranin V

GeneMGI:98289Synonyms: Sgne1, 7B2, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

4 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina vasculature morphology1 supporting datasetScg5em1(IMPC)MbphomozygoteEarly adult1.99x10-6 
abnormal behavior1 supporting datasetScg5em1(IMPC)MbphomozygoteEarly adult4.36x10-9 
hyperactivity5 supporting datasetsScg5em1(IMPC)MbphomozygoteEarly adult1.24x10-22 
decreased anxiety-related response1 supporting datasetScg5em1(IMPC)MbphomozygoteEarly adult7.29x10-11 
increased monocyte cell number1 supporting datasetScg5em1(IMPC)MbphomozygoteEarly adult7.19x10-5 
decreased thigmotaxis2 supporting datasetsScg5em1(IMPC)MbphomozygoteEarly adult4.17x10-9 
increased lean body mass1 supporting datasetScg5em1(IMPC)MbphomozygoteEarly adult9.36x10-5 
increased circulating alkaline phosphatase level1 supporting datasetScg5em1(IMPC)MbphomozygoteEarly adult3.07x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Scg5em1(IMPC)MbpIntra-exon deletionmouse
Scg5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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