Srsf5 | serine and arginine-rich splicing factor 5

GeneMGI:98287Synonyms: Sfrs5

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Pigmentation Integument Embryo Growth/size/body region Behavior/neurological Mortality/aging

13 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetSrsf5em1(IMPC)JhomozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance1 supporting datasetSrsf5em1(IMPC)JhomozygoteEarly adultN/A * 
hyperactivity6 supporting datasetsSrsf5em1(IMPC)JheterozygoteEarly adult2.07x10-10 
absent vibrissae1 supporting datasetSrsf5em1(IMPC)JheterozygoteEarly adult7.65x10-5 
abnormal vocalization1 supporting datasetSrsf5em1(IMPC)JheterozygoteEarly adult9.24x10-7 
abnormal coat/hair pigmentation1 supporting datasetSrsf5em1(IMPC)JheterozygoteEarly adult5.8x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Srsf5em1(IMPC)JExon Deletionmouse
Srsf5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Srsf5tm386283(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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