Rpl12 | ribosomal protein L12

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Mortality/aging Cardiovascular system Renal/urinary system

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Rpl12^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal spleen morphology	1 supporting dataset	Rpl12^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Rpl12^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Rpl12^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Rpl12^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
enlarged heart	2 supporting datasets	Rpl12^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Rpl12^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Rpl12^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Rpl12^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
enlarged spleen	1 supporting dataset	Rpl12^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Rpl12.

Associated images

Loading...

Histopathology

There is no histopathology data found for Rpl12.

IMPC related publications

Loading...

External links

No external links available for Rpl12.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Rpl12^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Rpl12^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes