Eprs1 | glutamyl-prolyl-tRNA synthetase 1
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Nervous system Respiratory system Mortality/aging
15 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Eprs1tm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| decreased prepulse inhibition | 1 supporting dataset | Eprs1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.01x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Eprs1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Eprs1tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Eprs1tm1b(EUCOMM)Hmgu | heterozygote | E9.5 | N/A * | ||
| abnormal lung morphology | 1 supporting dataset | Eprs1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | N/A * |
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External links
No external links available for Eprs1.
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| Eprs1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Eprs1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Eprs1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Eprs1tm272352(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |