Ptprz1 | protein tyrosine phosphatase receptor type Z, polypeptide 1

GeneMGI:97816Synonyms: PTPzeta, Rptpbeta, +6 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Hematopoietic system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged lymph nodes	1 supporting dataset	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	2 supporting datasets	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	2 supporting datasets	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
anophthalmia	1 supporting dataset	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
thin skin	1 supporting dataset	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Ptprz1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ptprz1.

Associated images

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Histopathology

There is no histopathology data found for Ptprz1.

IMPC related publications

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External links

No external links available for Ptprz1.

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*Ptprz1^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Ptprz1^{tm96469(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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