Pth | parathyroid hormone

GeneMGI:97799

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating calcium level	1 supporting dataset	Pth^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.72x10^-6
increased bone mineral density	1 supporting dataset	Pth^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.83x10^-5
abnormal retina morphology	1 supporting dataset	Pth^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.97x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pth.

Associated images

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Histopathology

There is no histopathology data found for Pth.

IMPC related publications

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External links

No external links available for Pth.

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*Pth^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pth^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pth^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Pth^{tm2(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse

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